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Attenuation in Nicotinic Acetylcholine Receptor α9 and α10 Subunit Double Knock-Out Mice of Experimental Autoimmune Encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is attenuated in nicotinic acetylcholine receptor (nAChR) α9 subunit knock-out (α9 KO) mice. However, protection is incomplete, raising questions about roles for related, nAChR α10 subunits in ionotropic or recently-revealed metabotropic contributions...

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Detalles Bibliográficos
Autores principales: Liu, Qiang, Li, Minshu, Whiteaker, Paul, Shi, Fu-Dong, Morley, Barbara J., Lukas, Ronald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995583/
https://www.ncbi.nlm.nih.gov/pubmed/31817275
http://dx.doi.org/10.3390/biom9120827