Wasabi Compound 6-(Methylsulfinyl) Hexyl Isothiocyanate Induces Cell Death with Coexisting Mitotic Arrest and Autophagy in Human Chronic Myelogenous Leukemia K562 Cells

A natural compound from Wasabia japonica, 6-(methylsulfinyl) hexyl isothiocyanate (6-MITC) was investigated for its anti-leukemia activity and mechanism of action. It was found that 6-MITC inhibited the viability of human chronic myelogenous leukemia K562 cells along with extensive mitotic arrest, s...

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Detalles Bibliográficos
Autores principales: Wu, Kun-Ming, Liao, Hui-Fen, Chi, Chih-Wen, Kou, Yu Ru, Chen, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995613/
https://www.ncbi.nlm.nih.gov/pubmed/31771225
http://dx.doi.org/10.3390/biom9120774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6995613/
https://www.ncbi.nlm.nih.gov/pubmed/31771225
http://dx.doi.org/10.3390/biom9120774

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