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High-throughput sequencing of pooled samples to determine community-level microbiome diversity

PURPOSE: Community-level interventions in cluster randomized controlled trials may alter the gut microbiome of individuals. The current method of estimating community diversities uses microbiome data obtained from multiple individual's specimens. Here we propose randomly pooling a number of mic...

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Detalles Bibliográficos
Autores principales: Ray, Kathryn J., Cotter, Sun Y., Arzika, Ahmed M., Kim, Jessica, Boubacar, Nameywa, Zhou, Zhaoxia, Zhong, Lina, Porco, Travis C., Keenan, Jeremy D., Lietman, Thomas M., Doan, Thuy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996001/
https://www.ncbi.nlm.nih.gov/pubmed/31635933
http://dx.doi.org/10.1016/j.annepidem.2019.09.002