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Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

Persistent viral infections subvert key elements of adaptive immunity. To compare germinal center (GC) B cell responses in chronic and acute lymphocytic choriomeningitis virus infection, we exploit activation-induced deaminase (AID) fate-reporter mice and perform adoptive B cell transfer experiments...

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Detalles Bibliográficos
Autores principales: Fallet, Bénédict, Hao, Yi, Florova, Marianna, Cornille, Karen, de los Aires, Alba Verge, Girelli Zubani, Giulia, Ertuna, Yusuf I., Greiff, Victor, Menzel, Ulrike, Hammad, Karim, Merkler, Doron, Reddy, Sai T., Weill, Jean-Claude, Reynaud, Claude-Agnès, Pinschewer, Daniel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996002/
https://www.ncbi.nlm.nih.gov/pubmed/31995746
http://dx.doi.org/10.1016/j.celrep.2019.12.023