Multiple myeloma-derived exosomes inhibit osteoblastic differentiation and improve IL-6 secretion of BMSCs from multiple myeloma

Bone marrow stromal cells (BMSCs) play a critical role in multiple myeloma (MM) pathogenesis by cell contact, and secretion of cytokines, growth factors and extracellular vesicles. Exosomes are secreted by almost all cell types and are recently reported to mediate local cell-to-cell cross-talk by tr...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoyun, Liu, Hui, Li, Yanqi, Shao, Qin, Chen, Jin, Song, Jia, Fu, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996099/
https://www.ncbi.nlm.nih.gov/pubmed/31784427
http://dx.doi.org/10.1136/jim-2019-001010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996099/
https://www.ncbi.nlm.nih.gov/pubmed/31784427
http://dx.doi.org/10.1136/jim-2019-001010

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