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Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS

OBJECTIVE: Approximately 35% of patients with amyotrophic lateral sclerosis (ALS) exhibit mild cognitive deficits in executive functions, language and fluency, without dementia. The precise pathology of these extramotor symptoms has remained unknown. This study aimed to determine the pathological co...

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Detalles Bibliográficos
Autores principales: Gregory, Jenna M, McDade, Karina, Bak, Thomas H, Pal, Suvankar, Chandran, Siddharthan, Smith, Colin, Abrahams, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996101/
https://www.ncbi.nlm.nih.gov/pubmed/31515300
http://dx.doi.org/10.1136/jnnp-2019-320807