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Executive, language and fluency dysfunction are markers of localised TDP-43 cerebral pathology in non-demented ALS
OBJECTIVE: Approximately 35% of patients with amyotrophic lateral sclerosis (ALS) exhibit mild cognitive deficits in executive functions, language and fluency, without dementia. The precise pathology of these extramotor symptoms has remained unknown. This study aimed to determine the pathological co...
Autores principales: | Gregory, Jenna M, McDade, Karina, Bak, Thomas H, Pal, Suvankar, Chandran, Siddharthan, Smith, Colin, Abrahams, Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996101/ https://www.ncbi.nlm.nih.gov/pubmed/31515300 http://dx.doi.org/10.1136/jnnp-2019-320807 |
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