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Genome-wide MNase hypersensitivity assay unveils distinct classes of open chromatin associated with H3K27me3 and DNA methylation in Arabidopsis thaliana

BACKGROUND: Regulation of transcription depends on interactions between cis-regulatory elements (CREs) and regulatory proteins. Active CREs are imbedded in open chromatin that are accessible to nucleases. Several techniques, including DNase-seq, which is based on nuclease DNase I, and ATAC-seq, whic...

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Detalles Bibliográficos
Autores principales: Zhao, Hainan, Zhang, Wenli, Zhang, Tao, Lin, Yuan, Hu, Yaodong, Fang, Chao, Jiang, Jiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996174/
https://www.ncbi.nlm.nih.gov/pubmed/32014062
http://dx.doi.org/10.1186/s13059-020-1927-5