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Tumor gene therapy by systemic delivery of plasmid DNA with cell‐penetrating peptides

Gene therapy is a prospective strategy for treating cancer. However, finding efficient and tumor‐specific gene delivery vectors remains an issue. Tumor responsive cell‐penetrating peptide (CPP) PepFect144 (PF144) has previously been shown to deliver reporter gene encoding plasmid DNA specifically in...

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Detalles Bibliográficos
Autores principales: Künnapuu, Kadri, Veiman, Kadi‐Liis, Porosk, Ly, Rammul, Evelin, Kiisholts, Kristina, Langel, Ülo, Kurrikoff, Kaido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996304/
https://www.ncbi.nlm.nih.gov/pubmed/32123824
http://dx.doi.org/10.1096/fba.1026