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ECDI‐fixed donor splenocytes prolong skin allograft survival by promoting M2 macrophage polarization and inducing regulatory T cells

Rejection is a common complication of allogeneic tissue transplantation. Fixation of splenocytes (SP) with 1‐ethyl‐3‐(3'‐dimethylaminopropyl)‐carbodiimide (ECDI) induces immune tolerance in recipients post‐transplantation; however, the mechanism underlying this effect remains unclear. Here, we...

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Detalles Bibliográficos
Autores principales: Zhou, Bo, Zhang, Yuan, Zhang, Dongliang, Zhang, Yun, Xie, Jiangang, Zhang, Xuexin, Ding, Jianke, Su, Yingjun, Guo, Shuzhong, Zhuang, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996306/
https://www.ncbi.nlm.nih.gov/pubmed/32123816
http://dx.doi.org/10.1096/fba.2019-00029