Manipulation of the tumor microenvironment by cytokine gene transfection enhances dendritic cell‐based immunotherapy

The tumor microenvironment strongly influences clinical outcomes of immunotherapy. By transfecting genes of relevant cytokines into tumor cells, we sought to manipulate the microenvironment so as to elicit activation of T helper type 1 (Th1) responses and the maturation of dendritic cells (DCs). Usi...

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Detalles Bibliográficos
Autores principales: Wijesekera, Daluthgamage Patsy Himali, Yuba, Eiji, De Silva, Nadeeka Harshini, Watanabe, Shun‐ichi, Tsukamoto, Masaya, Ichida, Chihiro, Izawa, Takeshi, Itoh, Kazuyuki, Kanegi, Ryoji, Hatoya, Shingo, Yamate, Jyoji, Inaba, Toshio, Sugiura, Kikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996313/
https://www.ncbi.nlm.nih.gov/pubmed/32123853
http://dx.doi.org/10.1096/fba.2019-00052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996313/
https://www.ncbi.nlm.nih.gov/pubmed/32123853
http://dx.doi.org/10.1096/fba.2019-00052

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