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A novel mutation alters the stability of PapA2 resulting in the complete abrogation of sulfolipids in clinical mycobacterial strains

The analysis of whole genomes has revealed specific geographical distribution of Mycobacterium tuberculosis (Mtb) strains across the globe suggestive of unique niche dependent adaptive mechanisms. We provide an important correlation of a genome‐based mutation to a molecular phenotype across two pred...

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Detalles Bibliográficos
Autores principales: Panchal, Vipul, Jatana, Nidhi, Malik, Anchal, Taneja, Bhupesh, Pal, Ravikant, Bhatt, Apoorva, Besra, Gurdyal S, Thukral, Lipi, Chaudhary, Sarika, Rao, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996325/
https://www.ncbi.nlm.nih.gov/pubmed/32123834
http://dx.doi.org/10.1096/fba.2018-00039