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Expression of mutant CHMP2B linked to neurodegeneration in humans disrupts circadian rhythms in Drosophila
Mutations in CHMP2B, an ESCRT‐III (endosomal sorting complexes required for transport) component, are associated with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Neurodegenerative disorders including FTD are also associated with a disruption in circadian rhythms, but the m...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996329/ https://www.ncbi.nlm.nih.gov/pubmed/32123847 http://dx.doi.org/10.1096/fba.2019-00042 |