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Expression of mutant CHMP2B linked to neurodegeneration in humans disrupts circadian rhythms in Drosophila

Mutations in CHMP2B, an ESCRT‐III (endosomal sorting complexes required for transport) component, are associated with frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Neurodegenerative disorders including FTD are also associated with a disruption in circadian rhythms, but the m...

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Detalles Bibliográficos
Autores principales: Lee, DaWon, Zheng, Xiaoyue, Shigemori, Kay, Krasniak, Christopher, Bin Liu, Jie, Tang, Chao, Kavaler, Joshua, Ahmad, S. Tariq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996329/
https://www.ncbi.nlm.nih.gov/pubmed/32123847
http://dx.doi.org/10.1096/fba.2019-00042