Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease

Bicaudal D1 (BICD1), an adaptor for the dynein‐dynactin motor complex, has been identified as a susceptibility gene in chronic obstructive pulmonary disease (COPD). Autophagy, an essential cellular homeostasis process, is defective in COPD, in which oxidative stress‐induced misfolded proteins accumu...

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Detalles Bibliográficos
Autores principales: Mercado, Nicolas, Colley, Thomas, Baker, Jonathan R., Vuppussetty, Chaitanya, Kono, Yuta, Clarke, Colin, Tooze, Sharon, Johansen, Terje, Barnes, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996363/
https://www.ncbi.nlm.nih.gov/pubmed/32123815
http://dx.doi.org/10.1096/fba.2018-00055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996363/
https://www.ncbi.nlm.nih.gov/pubmed/32123815
http://dx.doi.org/10.1096/fba.2018-00055

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