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Bicaudal D1 impairs autophagosome maturation in chronic obstructive pulmonary disease
Bicaudal D1 (BICD1), an adaptor for the dynein‐dynactin motor complex, has been identified as a susceptibility gene in chronic obstructive pulmonary disease (COPD). Autophagy, an essential cellular homeostasis process, is defective in COPD, in which oxidative stress‐induced misfolded proteins accumu...
Autores principales: | Mercado, Nicolas, Colley, Thomas, Baker, Jonathan R., Vuppussetty, Chaitanya, Kono, Yuta, Clarke, Colin, Tooze, Sharon, Johansen, Terje, Barnes, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996363/ https://www.ncbi.nlm.nih.gov/pubmed/32123815 http://dx.doi.org/10.1096/fba.2018-00055 |
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