IQGAP1 activates PLC‐δ1 by direct binding and moving along microtubule with DLC‐1 to cell surface

Phospholipase C (PLC)‐δ1, activated by p122RhoGTPase‐activating protein (GAP)/deleted in liver cancer‐1 (p122RhoGAP/DLC‐1), contributes to the coronary spastic angina (CSA) pathogenesis. The present study aims to further investigate the p122RhoGAP/DLC‐1 protein. We examined molecules assisting this...

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Detalles Bibliográficos
Autores principales: Tanaka, Makoto, Osanai, Tomohiro, Homma, Yoshimi, Hanada, Kenji, Okumura, Ken, Tomita, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996382/
https://www.ncbi.nlm.nih.gov/pubmed/32123844
http://dx.doi.org/10.1096/fba.2019-00020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996382/
https://www.ncbi.nlm.nih.gov/pubmed/32123844
http://dx.doi.org/10.1096/fba.2019-00020

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