Cargando…

IQGAP1 activates PLC‐δ1 by direct binding and moving along microtubule with DLC‐1 to cell surface

Phospholipase C (PLC)‐δ1, activated by p122RhoGTPase‐activating protein (GAP)/deleted in liver cancer‐1 (p122RhoGAP/DLC‐1), contributes to the coronary spastic angina (CSA) pathogenesis. The present study aims to further investigate the p122RhoGAP/DLC‐1 protein. We examined molecules assisting this...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanaka, Makoto, Osanai, Tomohiro, Homma, Yoshimi, Hanada, Kenji, Okumura, Ken, Tomita, Hirofumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996382/ https://www.ncbi.nlm.nih.gov/pubmed/32123844 http://dx.doi.org/10.1096/fba.2019-00020

Ejemplares similares

Enhanced p122RhoGAP/DLC-1 Expression Can Be a Cause of Coronary Spasm
por: Kinjo, Takahiko, et al.
Publicado: (2015)

IQGAP1 and IQGAP2 are Reciprocally Altered in Hepatocellular Carcinoma
por: White, Colin D, et al.
Publicado: (2010)

MDT-28/PLIN-1 mediates lipid droplet-microtubule interaction via DLC-1 in Caenorhabditis elegans
por: Xie, Kang, et al.
Publicado: (2019)

Endogenous IQGAP1 and IQGAP3 do not functionally interact with Ras
por: Morgan, Chase J., et al.
Publicado: (2019)

Role of IQGAP1 in Carcinogenesis
por: Wei, Tao, et al.
Publicado: (2021)

Osmotically evoked PLCδ1-dependent translocation of ΔN-TRPV1 channels in rat supraoptic neurons
por: Haan, Kirk D., et al.
Publicado: (2023)

DLC1 is the principal biologically-relevant down-regulated DLC family member in several cancers
por: Wang, Dunrui, et al.
Publicado: (2016)

CDK5 opens the way for DLC1
por: Short, Ben
Publicado: (2014)

An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells
por: Bartolini, Francesca, et al.
Publicado: (2016)

IQGAP1 is an oncogenic target in canine melanoma
por: Lee, Becky H., et al.
Publicado: (2017)

Correction for An mDia1-INF2 formin activation cascade facilitated by IQGAP1 regulates stable microtubules in migrating cells
Publicado: (2017)

IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression
por: Monteleon, Christine L., et al.
Publicado: (2015)

The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1
por: Liao, Yi-Chun, et al.
Publicado: (2007)

The Antithetic Roles of IQGAP2 and IQGAP3 in Cancers
por: Song, Fei, et al.
Publicado: (2023)

An Emerging Role for IQGAP1 in Regulating Protein Traffic
por: Osman, Mahasin
Publicado: (2010)

An emerging role for IQGAP1 in tight junction control
por: Tanos, Barbara E., et al.
Publicado: (2016)

The scaffold protein IQGAP1 is crucial for extravasation and metastasis
por: Hebert, Jess D., et al.
Publicado: (2020)

Cruising along Microtubule Highways: How Membranes Move through the Secretory Pathway
por: Bloom, George S., et al.
Publicado: (1998)

Functional analysis of the Drosophila RhoGAP Cv-c protein and its equivalence to the human DLC3 and DLC1 proteins
por: Sotillos, Sol, et al.
Publicado: (2018)

Ras GTPase-Activating-Like Protein IQGAP1 (IQGAP1) Promotes Breast Cancer Proliferation and Invasion and Correlates with Poor Clinical Outcomes
por: Zeng, Fanye, et al.
Publicado: (2018)

Direct observation shows superposition and large scale flexibility within cytoplasmic dynein motors moving along microtubules
por: Imai, Hiroshi, et al.
Publicado: (2015)

Hax1 regulate focal adhesion dynamics through IQGAP1
por: Ren, Xinyi, et al.
Publicado: (2023)

Significance of genetic variants in DLC1 and their association with hepatocellular carcinoma
por: XIE, CHENG-RONG, et al.
Publicado: (2015)

DLC1: a tumor suppressor that regulates Rho signaling
por: Tripathi, Brajendra K., et al.
Publicado: (2017)

Endothelial DLC1 is dispensable for liver and kidney function in mice
por: Tan, Ying, et al.
Publicado: (2020)

Aberrant DNA methylation of alternative promoter of DLC1 isoform 1 in meningiomas
por: Bujko, M., et al.
Publicado: (2016)

PKCδ Localization at the Membrane Increases Matrix Traction Force Dependent on PLCγ1/EGFR Signaling
por: Jamison, Joshua, et al.
Publicado: (2013)

Regulation of Spine Density and Morphology by IQGAP1 Protein Domains
por: Jausoro, Ignacio, et al.
Publicado: (2013)

IQGAP1 binds AMPK and is required for maximum AMPK activation
por: Hedman, Andrew C., et al.
Publicado: (2020)

Role of IQGAP1 in Papillomavirus-Associated Head and Neck Tumorigenesis
por: Wei, Tao, et al.
Publicado: (2021)

Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation
por: Brandt, Dominique T., et al.
Publicado: (2007)

IQGAP1 Negatively Regulates HIV-1 Gag Trafficking and Virion Production
por: Sabo, Yosef, et al.
Publicado: (2020)

1: Iqgap1 Signaling Promotes Foreign Body Response To Biomedical Implants
por: Sivaraj, Dharshan, et al.
Publicado: (2021)

MIP-1δ Activates NFATc1 and Enhances Osteoclastogenesis: Involvement of Both PLCγ2 and NFκB Signaling
por: Weber, Kristy L., et al.
Publicado: (2012)

Author Correction: Functional analysis of the Drosophila RhoGAP Cv-c protein and its equivalence to the human DLC3 and DLC1 proteins
por: Sotillos, Sol, et al.
Publicado: (2020)

DLC-1:a Rho GTPase-activating protein and tumour suppressor
por: Durkin, Marian E, et al.
Publicado: (2007)

CDK5 is a major regulator of the tumor suppressor DLC1
por: Tripathi, Brajendra K., et al.
Publicado: (2014)

LD Motif Recognition by Talin: Structure of the Talin-DLC1 Complex
por: Zacharchenko, Thomas, et al.
Publicado: (2016)

Mechanotransduction in talin through the interaction of the R8 domain with DLC1
por: Haining, Alexander William M., et al.
Publicado: (2018)

Regulation of white and brown adipocyte differentiation by RhoGAP DLC1
por: Sim, Choon Kiat, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_104mc7dm9qndos21sfgai4rmhe