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High‐level expression of STING restricts susceptibility to HBV by mediating type III IFN induction

Hepatitis B virus (HBV) is a hepatotropic DNA virus causing hepatic diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. To study HBV, human hepatoma HepG2 cells are currently used as an HBV infectious cell culture model worldwide. HepG2 cells exhibit susceptibility to...

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Detalles Bibliográficos
Autores principales: Dansako, Hiromichi, Imai, Hirotaka, Ueda, Youki, Satoh, Shinya, Shimotohno, Kunitada, Kato, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996391/
https://www.ncbi.nlm.nih.gov/pubmed/32123822
http://dx.doi.org/10.1096/fba.1022