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New technologies to introduce a catalytic function into antibodies: A unique human catalytic antibody light chain showing degradation of β‐amyloid molecule along with the peptidase activity

Since the discovery of a natural catalytic antibody in 1989, many catalytic antibodies targeting peptides, nucleotides, virus and bacterial proteins, and many molecules have been prepared. Although catalytic antibodies should have features superior to non‐catalytic monoclonal antibodies, the reports...

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Detalles Bibliográficos
Autores principales: Hifumi, Emi, Taguchi, Hiroaki, Toorisaka, Eiichi, Uda, Taizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996398/
https://www.ncbi.nlm.nih.gov/pubmed/32123823
http://dx.doi.org/10.1096/fba.1025