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S‐Nitrosated alpha‐1‐acid glycoprotein exhibits antibacterial activity against multidrug‐resistant bacteria strains and synergistically enhances the effect of antibiotics

Alpha‐1‐acid glycoprotein (AGP) is a major acute‐phase protein. Biosynthesis of AGP increases markedly during inflammation and infection, similar to nitric oxide (NO) biosynthesis. AGP variant A (AGP) contains a reduced cysteine (Cys149). Previously, we reported that S‐nitrosated AGP (SNO‐AGP) synth...

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Detalles Bibliográficos
Autores principales: Ishima, Yu, Watanabe, Kaori, Chuang, Victor T. G., Takeda, Iyo, Kuroda, Teruo, Ogawa, Wakano, Watanabe, Hiroshi, Iwao, Yasunori, Ishida, Tatsuhiro, Otagiri, Masaki, Maruyama, Toru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996401/
https://www.ncbi.nlm.nih.gov/pubmed/32123826
http://dx.doi.org/10.1096/fba.1018