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Dexamethasone promotes mesenchymal stem cell apoptosis and inhibits osteogenesis by disrupting mitochondrial dynamics

Long‐term or heavy use of glucocorticoids can cause severe necrosis of the femoral head, but the underlying mechanisms are still unclear. Recent studies have found that mitochondrial dynamics play an important role in femoral head necrosis. Here, we investigated the effect of dexamethasone on the mi...

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Detalles Bibliográficos
Autores principales: Ma, Liang, Feng, Xiaobo, Wang, Kun, Song, Yu, Luo, Rongjin, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996403/
https://www.ncbi.nlm.nih.gov/pubmed/31788976
http://dx.doi.org/10.1002/2211-5463.12771