Cyclosporine A inhibits MRTF‐SRF signaling through Na(+)/K(+) ATPase inhibition and actin remodeling

Calcineurin inhibitors (CNI) are the pillars of immunosuppression in transplantation. However, they display a potent nephrotoxicity whose mechanisms remained widely unsolved. We used an untargeted quantitative proteomic approach (iTRAQ technology) to highlight new targets of CNI in renal proximal tu...

Descripción completa

Detalles Bibliográficos
Autores principales: Burat, Bastien, Faucher, Quentin, Čechová, Petra, Arnion, Hélène, Di Meo, Florent, Sauvage, François‐Ludovic, Marquet, Pierre, Essig, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996406/
https://www.ncbi.nlm.nih.gov/pubmed/32123851
http://dx.doi.org/10.1096/fba.2019-00027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996406/
https://www.ncbi.nlm.nih.gov/pubmed/32123851
http://dx.doi.org/10.1096/fba.2019-00027

Ejemplares similares