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Cyclosporine A inhibits MRTF‐SRF signaling through Na(+)/K(+) ATPase inhibition and actin remodeling

Calcineurin inhibitors (CNI) are the pillars of immunosuppression in transplantation. However, they display a potent nephrotoxicity whose mechanisms remained widely unsolved. We used an untargeted quantitative proteomic approach (iTRAQ technology) to highlight new targets of CNI in renal proximal tu...

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Detalles Bibliográficos
Autores principales:	Burat, Bastien, Faucher, Quentin, Čechová, Petra, Arnion, Hélène, Di Meo, Florent, Sauvage, François‐Ludovic, Marquet, Pierre, Essig, Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996406/ https://www.ncbi.nlm.nih.gov/pubmed/32123851 http://dx.doi.org/10.1096/fba.2019-00027

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