Reversible Small Molecule Inhibitors of MAO A and MAO B with Anilide Motifs

BACKGROUND: Ligands consisting of two aryl moieties connected via a short spacer were shown to be potent inhibitors of monoamine oxidases (MAO) A and B, which are known as suitable targets in treatment of neurological diseases. Based on this general blueprint, we synthesized a series of 66 small aro...

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Detalles Bibliográficos
Autores principales: Hagenow, Jens, Hagenow, Stefanie, Grau, Kathrin, Khanfar, Mohammad, Hefke, Lena, Proschak, Ewgenij, Stark, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996489/
https://www.ncbi.nlm.nih.gov/pubmed/32099324
http://dx.doi.org/10.2147/DDDT.S236586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996489/
https://www.ncbi.nlm.nih.gov/pubmed/32099324
http://dx.doi.org/10.2147/DDDT.S236586

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