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Fluorouracil sensitivity in a head and neck squamous cell carcinoma with a somatic DPYD structural variant

Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers worldwide and represents a heterogeneous group of tumors, the majority of which are treated with a combination of surgery, radiation, and chemotherapy. Fluoropyrimidine (5-FU) and its oral prodrug, capecitabine, are comm...

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Detalles Bibliográficos
Autores principales: Majounie, Elisa, Wee, Kathleen, Williamson, Laura M., Jones, Martin R., Pleasance, Erin, Lim, Howard J., Ho, Cheryl, Renouf, Daniel J., Yip, Stephen, Jones, Steven J.M., Marra, Marco A., Laskin, Janessa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996515/
https://www.ncbi.nlm.nih.gov/pubmed/31871216
http://dx.doi.org/10.1101/mcs.a004713