Development of a Novel Controlled-Release Tablet of Pregabalin: Formulation Variation and Pharmacokinetics in Dogs and Humans

BACKGROUND: Novel three-layered (TL) tablet systems were compared with both monolithic matrix (MM) formulations and a commercial immediate-release (IR) capsule to develop once-a-day (OAD) pregabalin tablets. METHODS: The physical properties of the TL tablets, including dissolution and swelling rates...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Kyung Hun, Lim, Seo Hyun, Shim, Cho Rok, Park, Junsung, Song, Woo Heon, Kwon, Min Chang, Lee, Jong Hyuk, Park, Jun Sang, Choi, Han-Gon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996546/
https://www.ncbi.nlm.nih.gov/pubmed/32099329
http://dx.doi.org/10.2147/DDDT.S222505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996546/
https://www.ncbi.nlm.nih.gov/pubmed/32099329
http://dx.doi.org/10.2147/DDDT.S222505

Ejemplares similares