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microRNA-182 Negatively Influences the Neuroprotective Effect of Apelin Against Neuronal Injury in Epilepsy

PURPOSE: To explore the neuroprotective effects and mechanisms of Apelin (APLN), and to study the regulation of APLN expression by microRNA (miRNA) in epilepsy. MATERIALS AND METHODS: In vitro and in vivo epileptic models were established with hippocampal neurons and Wistar rats. Apoptosis of neuron...

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Detalles Bibliográficos
Autores principales: Dong, Han, Dong, Bin, Zhang, Na, Liu, Songyan, Zhao, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996621/
https://www.ncbi.nlm.nih.gov/pubmed/32099369
http://dx.doi.org/10.2147/NDT.S238826