Rational Engineered C-Acyltransferase Transforms Sterically Demanding Acyl Donors

[Image: see text] The biocatalytic Friedel–Crafts acylation has been identified recently for the acetylation of resorcinol using activated acetic acid esters for the synthesis of acetophenone derivatives catalyzed by an acyltransferase. Because the wild-type enzyme is limited to acetic and propionic...

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Detalles Bibliográficos
Autores principales: Żądło-Dobrowolska, Anna, Hammerer, Lucas, Pavkov-Keller, Tea, Gruber, Karl, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996649/
https://www.ncbi.nlm.nih.gov/pubmed/32030315
http://dx.doi.org/10.1021/acscatal.9b04617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996649/
https://www.ncbi.nlm.nih.gov/pubmed/32030315
http://dx.doi.org/10.1021/acscatal.9b04617

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