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Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas

Claudin (CLDN)-4 expression has been associated with malignancy in various cancers. When CLDN4 expression was examined in oral squamous cell carcinoma (OSCC), 22 out of 57 (39%) cases showed immunoreactivity in the nucleus. Nuclear CLDN4-positive cases showed a stronger correlation with cancer progr...

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Detalles Bibliográficos
Autores principales: Nakashima, Chie, Yamamoto, Kazuhiko, Kishi, Shingo, Sasaki, Takamitsu, Ohmori, Hitoshi, Fujiwara-Tani, Rina, Mori, Shiori, Kawahara, Isao, Nishiguchi, Yukiko, Mori, Takuya, Kondoh, Masuo, Luo, Yi, Kirita, Tadaaki, Kuniyasu, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996904/
https://www.ncbi.nlm.nih.gov/pubmed/32064037
http://dx.doi.org/10.18632/oncotarget.27424