Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila

Unpaired ligands are secreted signals that act via a GP130-like receptor, domeless, to activate JAK/STAT signalling in Drosophila. Like many mammalian cytokines, unpaireds can be activated by infection and other stresses and can promote insulin resistance in target tissues. However, the importance o...

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Detalles Bibliográficos
Autores principales: Kierdorf, Katrin, Hersperger, Fabian, Sharrock, Jessica, Vincent, Crystal M, Ustaoglu, Pinar, Dou, Jiawen, Gyoergy, Attila, Groß, Olaf, Siekhaus, Daria E, Dionne, Marc S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996930/
https://www.ncbi.nlm.nih.gov/pubmed/31944178
http://dx.doi.org/10.7554/eLife.51595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996930/
https://www.ncbi.nlm.nih.gov/pubmed/31944178
http://dx.doi.org/10.7554/eLife.51595

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