Compromised steady‐state germinal center activity with age in nonhuman primates

Age‐related reductions in vaccine‐induced B cells in aging indicate that germinal centers (GCs), the anatomical site where the development of humoral responses takes place, may lose efficacy with age. We have investigated the baseline follicular and GC composition in nonhuman primates (NHPs) with re...

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Detalles Bibliográficos
Autores principales: Shankwitz, Kimberly, Pallikkuth, Suresh, Sirupangi, Tirupataiah, Kirk Kvistad, Daniel, Russel, Kyle Blaine, Pahwa, Rajendra, Gama, Lucio, Koup, Richard A., Pan, Li, Villinger, Francois, Pahwa, Savita, Petrovas, Constantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996951/
https://www.ncbi.nlm.nih.gov/pubmed/31840398
http://dx.doi.org/10.1111/acel.13087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996951/
https://www.ncbi.nlm.nih.gov/pubmed/31840398
http://dx.doi.org/10.1111/acel.13087

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