Early removal of senescent cells protects retinal ganglion cells loss in experimental ocular hypertension

Experimental ocular hypertension induces senescence of retinal ganglion cells (RGCs) that mimics events occurring in human glaucoma. Senescence‐related chromatin remodeling leads to profound transcriptional changes including the upregulation of a subset of genes that encode multiple proteins collect...

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Detalles Bibliográficos
Autores principales: Rocha, Lorena Raquel, Nguyen Huu, Viet Anh, Palomino La Torre, Claudia, Xu, Qianlan, Jabari, Mary, Krawczyk, Michal, Weinreb, Robert N., Skowronska‐Krawczyk, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996954/
https://www.ncbi.nlm.nih.gov/pubmed/31867890
http://dx.doi.org/10.1111/acel.13089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996954/
https://www.ncbi.nlm.nih.gov/pubmed/31867890
http://dx.doi.org/10.1111/acel.13089

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