A genome‐wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells

To ensure proper transmission of genetic information, cells need to preserve and faithfully replicate their genome, and failure to do so leads to genome instability, a hallmark of both cancer and aging. Defects in genes involved in guarding genome stability cause several human progeroid syndromes, a...

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Detalles Bibliográficos
Autores principales: Novarina, Daniele, Janssens, Georges E., Bokern, Koen, Schut, Tim, van Oerle, Noor C., Kazemier, Hinke G., Veenhoff, Liesbeth M., Chang, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960/
https://www.ncbi.nlm.nih.gov/pubmed/31854076
http://dx.doi.org/10.1111/acel.13084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996960/
https://www.ncbi.nlm.nih.gov/pubmed/31854076
http://dx.doi.org/10.1111/acel.13084

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