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Base excision repair but not DNA double‐strand break repair is impaired in aged human adipose‐derived stem cells
The decline in DNA repair capacity contributes to the age‐associated decrease in genome integrity in somatic cells of different species. However, due to the lack of clinical samples and appropriate tools for studying DNA repair, whether and how age‐associated changes in DNA repair result in a loss o...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996963/ https://www.ncbi.nlm.nih.gov/pubmed/31782607 http://dx.doi.org/10.1111/acel.13062 |