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Investigation of HIV-1 Gag binding with RNAs and lipids using Atomic Force Microscopy

Atomic Force Microscopy was utilized to study the morphology of Gag, ΨRNA, and their binding complexes with lipids in a solution environment with 0.1Å vertical and 1nm lateral resolution. TARpolyA RNA was used as a RNA control. The lipid used was phospha-tidylinositol-(4,5)-bisphosphate (PI(4,5)P2)....

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Detalles Bibliográficos
Autores principales: Chen, Shaolong, Xu, Jun, Liu, Mingyue, Rao, A. L. N., Zandi, Roya, Gill, Sarjeet S., Mohideen, Umar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996966/
https://www.ncbi.nlm.nih.gov/pubmed/32015565
http://dx.doi.org/10.1371/journal.pone.0228036