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Impact of clinicopathologic features on leptomeningeal metastasis from lung adenocarcinoma and treatment efficacy with epidermal growth factor receptor tyrosine kinase inhibitor

BACKGROUND: We investigated the risk factors for leptomeningeal carcinomatosis (LMC) and compared clinical efficacies of various treatment modalities including intrathecal (IT) chemotherapy in patients with lung adenocarcinoma harboring epidermal growth factor receptor (EGFR) mutations. METHODS: Usi...

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Detalles Bibliográficos
Autores principales: Kwon, Byoung Soo, Cho, Young Hyun, Yoon, Shin‐Kyo, Lee, Dae Ho, Kim, Sang‐We, Kwon, Do Hoon, Lee, Jae Cheol, Choi, Chang‐Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6996974/
https://www.ncbi.nlm.nih.gov/pubmed/31910497
http://dx.doi.org/10.1111/1759-7714.13296