Combination of aloin and metformin enhances the antitumor effect by inhibiting the growth and invasion and inducing apoptosis and autophagy in hepatocellular carcinoma through PI3K/AKT/mTOR pathway

Hepatocellular carcinoma (HCC) is a devastating and highly metastatic cancer worldwide. Metformin (MET) is the priority drug for treatment of type 2 diabetes; however, it possesses multiple biological effects like anticancer and hepatoprotective activity. Herein, we examined the effects of aloin (ba...

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Detalles Bibliográficos
Autores principales: Sun, Ruijie, Zhai, Ruiren, Ma, Changlin, Miao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997051/
https://www.ncbi.nlm.nih.gov/pubmed/31830378
http://dx.doi.org/10.1002/cam4.2723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997051/
https://www.ncbi.nlm.nih.gov/pubmed/31830378
http://dx.doi.org/10.1002/cam4.2723

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