Establishment of patient‐derived xenograft model of peritoneal mucinous carcinomatosis with signet ring cells and in vivo study on the efficacy and toxicity of intraperitoneal injection of 5‐fluorouracil

BACKGROUND: Pseudomyxoma peritonei (PMP) is an indolent malignancy and insensitive to systemic chemotherapy. The authors established patient‐derived xenograft (PDX) model of PMP, and evaluated the efficacy and toxicity of intraperitoneal (i.p.) administration of 5‐fluorouracil (5‐FU) in this model....

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Detalles Bibliográficos
Autores principales: Lin, Yu‐Lin, Zhang, Jue, Yan, Feng‐Cai, Jiang, Xi, Ma, Ru, Yang, Zhi‐Ran, Xu, Hong‐Bin, Peng, Zheng, Chen, Qian, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997068/
https://www.ncbi.nlm.nih.gov/pubmed/31814323
http://dx.doi.org/10.1002/cam4.2766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997068/
https://www.ncbi.nlm.nih.gov/pubmed/31814323
http://dx.doi.org/10.1002/cam4.2766

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