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EGFR enhances the stemness and progression of oral cancer through inhibiting autophagic degradation of SOX2

Epidermal growth factor receptor (EGFR) is highly expressed in head and neck squamous cell carcinoma (HNSCC) and correlates with poor prognosis. EGFR has been demonstrated to be associated with cancer stem cell traits in HNSCC. However, the underlying molecular mechanism is far from elucidated. Here...

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Detalles Bibliográficos
Autores principales: Lv, Xiao‐Xi, Zheng, Xiao‐Yu, Yu, Jiao‐Jiao, Ma, Hua‐Rui, Hua, Cheng, Gao, Run‐Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997074/
https://www.ncbi.nlm.nih.gov/pubmed/31823521
http://dx.doi.org/10.1002/cam4.2772