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The role of DOT1L in the proliferation and prognosis of gastric cancer

Background: Disruptor of telomeric silencing-1-like (DOT1L), a methyltransferase of H3K79, was observed to be amplified and overexpressed in certain malignancies. This work was aimed at investigating the differences in DOT1L expression and its regulatory mechanism in gastric cancer (GC) and healthy...

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Detalles Bibliográficos
Autores principales: Song, Zaozhi, Wei, Zhuoli, Wang, Qingkang, Zhang, Xinxin, Tao, Xiaoying, Wu, Nan, Liu, Xue, Qian, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997103/
https://www.ncbi.nlm.nih.gov/pubmed/31939604
http://dx.doi.org/10.1042/BSR20193515