The Trp triad within the V-domain of the receptor for advanced glycation end products modulates folding, stability and ligand binding

The receptor for advanced glycation end products (RAGE) recognizes damage-associated molecular patterns (DAMPs) and plays a critical role for the innate immune response and sterile tissue inflammation. RAGE overexpression is associated with diabetic complications, neurodegenerative diseases and cert...

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Detalles Bibliográficos
Autores principales: Indurthi, Venkata S.K., Jensen, Jaime L., Leclerc, Estelle, Sinha, Sangita, Colbert, Christopher L., Vetter, Stefan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997106/
https://www.ncbi.nlm.nih.gov/pubmed/31912881
http://dx.doi.org/10.1042/BSR20193360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997106/
https://www.ncbi.nlm.nih.gov/pubmed/31912881
http://dx.doi.org/10.1042/BSR20193360

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