Cargando…

The Trp triad within the V-domain of the receptor for advanced glycation end products modulates folding, stability and ligand binding

The receptor for advanced glycation end products (RAGE) recognizes damage-associated molecular patterns (DAMPs) and plays a critical role for the innate immune response and sterile tissue inflammation. RAGE overexpression is associated with diabetic complications, neurodegenerative diseases and cert...

Descripción completa

Detalles Bibliográficos
Autores principales:	Indurthi, Venkata S.K., Jensen, Jaime L., Leclerc, Estelle, Sinha, Sangita, Colbert, Christopher L., Vetter, Stefan W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997106/ https://www.ncbi.nlm.nih.gov/pubmed/31912881 http://dx.doi.org/10.1042/BSR20193360

Ejemplares similares

Hypoxia and the Receptor for Advanced Glycation End Products (RAGE) Signaling in Cancer
por: Taneja, Sakshi, et al.
Publicado: (2021)

Non-conservation of folding rates in the thioredoxin family reveals degradation of ancestral unassisted-folding
por: Gamiz-Arco, Gloria, et al.
Publicado: (2019)

RAGE Up-Regulation Differently Affects Cell Proliferation and Migration in Pancreatic Cancer Cells
por: Swami, Priyanka, et al.
Publicado: (2020)

Comparing the folding landscapes of evolutionarily divergent procaspase-3
por: Yao, Liqi, et al.
Publicado: (2022)

Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels
por: Ben-Abu, Yuval, et al.
Publicado: (2023)

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
por: Vivoli, Mirella, et al.
Publicado: (2014)

Glycation affects fibril formation of Aβ peptides
por: Emendato, Alessandro, et al.
Publicado: (2018)

Agonist efficiency links binding and gating in a nicotinic receptor
por: Indurthi, Dinesh C, et al.
Publicado: (2023)

Protein–ligand interactions investigated by thermal shift assays (TSA) and dual polarization interferometry (DPI)
por: Grøftehauge, Morten K., et al.
Publicado: (2015)

Topological polymorphism of nucleosome fibers and folding of chromatin
por: Zhurkin, Victor B., et al.
Publicado: (2021)

An Extended Active-site Motif Controls the Reactivity of the Thioredoxin Fold
por: Mavridou, Despoina A. I., et al.
Publicado: (2014)

Anti-antimicrobial Peptides: FOLDING-MEDIATED HOST DEFENSE ANTAGONISTS
por: Ryan, Lloyd, et al.
Publicado: (2013)

Folding Dynamics and Pathways of the Trp-Cage Miniproteins
por: Byrne, Aimee, et al.
Publicado: (2014)

Loading history changes the morphology and compressive force-induced expression of receptor activator of nuclear factor kappa B ligand/osteoprotegerin in MLO-Y4 osteocytes
por: Wang, Ziyi, et al.
Publicado: (2020)

Structural basis of cell-surface signaling by a conserved sigma regulator in Gram-negative bacteria
por: Jensen, Jaime L., et al.
Publicado: (2020)

Inhibition of the Receptor for Advanced Glycation End Products Enhances the Cytotoxic Effect of Gemcitabine in Murine Pancreatic Tumors
por: Swami, Priyanka, et al.
Publicado: (2021)

Towards a barrier height benchmark set for biologically relevant systems
por: Kromann, Jimmy C., et al.
Publicado: (2016)

Prediction of pKa values using the PM6 semiempirical method
por: Kromann, Jimmy C., et al.
Publicado: (2016)

ProCS15: a DFT-based chemical shift predictor for backbone and Cβ atoms in proteins
por: Larsen, Anders S., et al.
Publicado: (2015)

Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins
por: Crabtree, Michael D., et al.
Publicado: (2018)

Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms
por: Huffer, Katherine E, et al.
Publicado: (2020)

Dynamic Folding Pathway Models of the Trp-Cage Protein
por: Lee, In-Ho, et al.
Publicado: (2013)

Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates
por: Ivanovic, Tijana, et al.
Publicado: (2013)

Effects of ligand distribution on receptor-diffusion-mediated cellular uptake of nanoparticles
por: Li, Long, et al.
Publicado: (2017)

Conformational Response to Ligand Binding in Phosphomannomutase2: INSIGHTS INTO INBORN GLYCOSYLATION DISORDER
por: Andreotti, Giuseppina, et al.
Publicado: (2014)

Ligand-receptor-mediated attachment of lipid vesicles to a supported lipid bilayer
por: Zhdanov, Vladimir P.
Publicado: (2020)

Cannabinoid Ligands Targeting TRP Channels
por: Muller, Chanté, et al.
Publicado: (2019)

A white-box model of S-shaped and double S-shaped single-species population growth
por: Kalmykov, Lev V., et al.
Publicado: (2015)

Using stiffness to assess injury risk: comparison of methods for quantifying stiffness and their reliability in triathletes
por: Lorimer, Anna V., et al.
Publicado: (2018)

Role of tryptophan residues of Erv1: Trp(95) and Trp(183) are important for its folding and oxidase function
por: Wang, Qi, et al.
Publicado: (2015)

Long range Trp-Trp interaction initiates the folding pathway of a pro-angiogenic β-hairpin peptide
por: Diana, Donatella, et al.
Publicado: (2015)

Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of d-Amino Acid Deacylase
por: Bhatt, Tarun Kumar, et al.
Publicado: (2010)

Conformational Selection and Submillisecond Dynamics of the Ligand-binding Domain of the N-Methyl-d-aspartate Receptor
por: Dolino, Drew M., et al.
Publicado: (2016)

The development of curvature in the porcine radioulna
por: Pantinople, Jess, et al.
Publicado: (2017)

Divergent kinase WNG1 is regulated by phosphorylation of an atypical activation sub-domain
por: Dewangan, Pravin S., et al.
Publicado: (2022)

Quantifying Mixing using Magnetic Resonance Imaging
por: Tozzi, Emilio J., et al.
Publicado: (2012)

Joint-level energetics differentiate isoinertial from speed-power resistance training—a Bayesian analysis
por: Liew, Bernard X.W., et al.
Publicado: (2018)

Classical lepidopteran wing scale colouration in the giant butterfly-moth Paysandisia archon
por: Stavenga, Doekele G., et al.
Publicado: (2018)

Thermal fluctuations of immature SOD1 lead to separate folding and misfolding pathways
por: Sekhar, Ashok, et al.
Publicado: (2015)

The influence of various regions of the FOXP2 sequence on its structure and DNA-binding function
por: Thulo, Monare, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_crhjicv750f13fu3u3efc11qhe