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Live Birth in Sex-Reversed XY Mice Lacking the Nuclear Receptor Dax1

The nuclear hormone receptor Dax1 functions during development as a testes-determining gene. However, the phenotype of male mice lacking Dax1 is strain-dependent due to the background-specific abundance of male-determining Sry gene-transcripts. We hypothesised that inter-individual variation in Sry...

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Detalles Bibliográficos
Autores principales: Fernandes-Freitas, Isabel, Milona, Alexandra, Murphy, Kevin G., Dhillo, Waljit S., Owen, Bryn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997165/
https://www.ncbi.nlm.nih.gov/pubmed/32015477
http://dx.doi.org/10.1038/s41598-020-58788-9