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Two-stage electro–mechanical coupling of a K(V) channel in voltage-dependent activation

In voltage-gated potassium (K(V)) channels, the voltage-sensing domain (VSD) undergoes sequential activation from the resting state to the intermediate state and activated state to trigger pore opening via electro–mechanical (E–M) coupling. However, the spatial and temporal details underlying E–M co...

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Detalles Bibliográficos
Autores principales: Hou, Panpan, Kang, Po Wei, Kongmeneck, Audrey Deyawe, Yang, Nien-Du, Liu, Yongfeng, Shi, Jingyi, Xu, Xianjin, White, Kelli McFarland, Zaydman, Mark A., Kasimova, Marina A., Seebohm, Guiscard, Zhong, Ling, Zou, Xiaoqin, Tarek, Mounir, Cui, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997178/
https://www.ncbi.nlm.nih.gov/pubmed/32015334
http://dx.doi.org/10.1038/s41467-020-14406-w