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Two-stage electro–mechanical coupling of a K(V) channel in voltage-dependent activation
In voltage-gated potassium (K(V)) channels, the voltage-sensing domain (VSD) undergoes sequential activation from the resting state to the intermediate state and activated state to trigger pore opening via electro–mechanical (E–M) coupling. However, the spatial and temporal details underlying E–M co...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997178/ https://www.ncbi.nlm.nih.gov/pubmed/32015334 http://dx.doi.org/10.1038/s41467-020-14406-w |