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Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis

PURPOSE: Tumor microenvironment, including inflammatory cells, adipocytes and extracellular matrix constituents such as hyaluronan (HA), impacts on cancer progression. Systemic metabolism also influences tumor growth e.g. obesity and type 2 diabetes (T2D) are risk factors for breast cancer. Here, in...

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Detalles Bibliográficos
Autores principales: Tiainen, Satu, Masarwah, Amro, Oikari, Sanna, Rilla, Kirsi, Hämäläinen, Kirsi, Sudah, Mazen, Sutela, Anna, Vanninen, Ritva, Ikonen, Juho, Tammi, Raija, Tammi, Markku, Auvinen, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997252/
https://www.ncbi.nlm.nih.gov/pubmed/31720917
http://dx.doi.org/10.1007/s10549-019-05491-7