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The mTOR Inhibitor Rapamycin Prevents General Anesthesia-Induced Changes in Synaptic Transmission and Mitochondrial Respiration in Late Postnatal Mice

Preclinical animal studies have continuously reported the possibility of long-lasting neurotoxic effects after general anesthesia in young animals. Such studies also show that the neurological changes induced by anesthesia in young animals differ by their neurodevelopmental stage. Exposure to anesth...

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Detalles Bibliográficos
Autores principales: Ju, Xianshu, Ryu, Min Jeong, Cui, Jianchen, Lee, Yulim, Park, Sangil, Hong, Boohwi, Yoo, Sungho, Lee, Won Hyung, Shin, Yong Sup, Yoon, Seok-Hwa, Kweon, Gi Ryang, Kim, Yoon Hee, Ko, Youngkwon, Heo, Jun Young, Chung, Woosuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997293/
https://www.ncbi.nlm.nih.gov/pubmed/32047423
http://dx.doi.org/10.3389/fncel.2020.00004