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A micro-XRT image analysis and machine learning methodology for the characterisation of multi-particulate capsule formulations
The application of X-ray microtomography for quantitative structural analysis of pharmaceutical multi-particulate systems was demonstrated for commercial capsules, each containing approximately 300 formulated ibuprofen pellets. The implementation of a marker-supported watershed transformation enable...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997304/ https://www.ncbi.nlm.nih.gov/pubmed/32025658 http://dx.doi.org/10.1016/j.ijpx.2020.100041 |