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Inhibition of Serine Protease Activity Protects Against High Fat Diet-Induced Inflammation and Insulin Resistance

Recent evidence suggests that enhanced protease-mediated inflammation may promote insulin resistance and result in diabetes. This study tested the hypothesis that serine protease plays a pivotal role in type 2 diabetes, and inhibition of serine protease activity prevents hyperglycemia in diabetic an...

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Detalles Bibliográficos
Autores principales: Kuo, Chin-Sung, Chen, Jia-Shiong, Lin, Liang-Yu, Schmid-Schönbein, Geert W., Chien, Shu, Huang, Po-Hsun, Chen, Jaw-Wen, Lin, Shing-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997356/
https://www.ncbi.nlm.nih.gov/pubmed/32015418
http://dx.doi.org/10.1038/s41598-020-58361-4