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Inducible expression of Wnt7b promotes bone formation in aged mice and enhances fracture healing
There remain unmet clinical needs for safe and effective bone anabolic therapies to treat aging-related osteoporosis and to improve fracture healing in cases of nonunion or delayed union. Wnt signaling has emerged as a promising target pathway for developing novel bone anabolic drugs. Although neutr...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6997361/ https://www.ncbi.nlm.nih.gov/pubmed/32047703 http://dx.doi.org/10.1038/s41413-019-0081-8 |